
Neisseria
Molecular Mechanisms of Pathogenesis
by C. A. Genco
270 pages· 2010· ISBN 9781904455516
About
Neisseria gonorrhoeae and Nesseria meningitidis are Gram-negative diplococci. N. gonorrhoeae is the causative agent of gonorrhoeae and is transmitted via sexual contact. N. meningitidis is transmitted via respiratory droplets leading to colonization of the nasopharynx and can cause meningitis and septicemia.This important reference volume provides research scientists, advanced students, clinicians, and other professionals with a comprehensive update on the current understanding of the molecular mechanisms of pathogenesis in Neisseria. The editors have assembled a team of highly regarded scientists, over 40 contributors, to describe the latest, up-to-date research, theory and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies and mechanisms of cellular invasion. A section on the host response to neisserial infection covers inate immunity, complement, apoptosis, and acquired immunity while a section devoted to clinical correlation deals with vaccine development, epidemiology and antibiotic resistance
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