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The fourth edition is an up-dated coverage of every conceivable aspect of the modern-day management of contact dermatitis. Both irritant and allergic contact dermatitis are covered fully and clearly, special emphasis being given to immunolgical mechanisms, molecular aspects of sensitizers, atypical clinical forms, reactions to medicaments, occupational and environmental aspects. Several new chapters focus on fragrances, hair dyes, and methods for quantitative risk assessment of allergens and irritants. The textbook also covers epidemiology, the histopathology and ultrastructure of contact dermatitis, methods of skin-testing other than patch testing, skin penetration, and principles of prevention and protection. Legislative regulations on contact allergens and legal aspects of worker's compensation for occupational dermatitis are dealt with as well as the expanding use of computers in surveillance sytems and practical management of patients. For optimizing the diagnostic appro.

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