Role of the Mitotic Spindle in the Equal Segregation of an Extrachromosomal Element in Saccharomyces Cerevisiae

Role of the Mitotic Spindle in the Equal Segregation of an Extrachromosomal Element in Saccharomyces Cerevisiae

243 pages· 2008· ISBN 9780549779117
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The Saccharomyces cerevisiae plasmid, 2 micron circle, resides in the yeast nucleus at a high copy number. It provides no apparent growth advantage to its host, nor imposes any significant growth disadvantage. The plasmid is an excellent paradigm for studying mechanisms utilized in the persistence of a eukaryotic selfish DNA element that is selectively neutral.

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